What is really driving inflammation in your body
By Dr. Marisa Quevedo, D.C. · August 19, 2026
Inflammation gets talked about as though it were the disease. It is not. It is a response, which means that if it will not settle down, something is still asking for it. The useful question is never "how do I lower inflammation," it is "what is my body responding to."
What are the most common drivers?
In practice, chronic inflammation almost always traces back to a short list: the gut, what you are eating, sleep debt, chronic stress, sitting still, and stored visceral fat. Most people have two or three of these running at once, which is why single fixes disappoint.
The gut lining
This is where I start most often. When the intestinal barrier becomes more permeable than it should be, material that belongs inside the gut interacts with the immune system on the other side. The immune response that follows is systemic, which is why the symptom often shows up nowhere near your abdomen.
Foods that are a problem for you specifically
Not a universal list, and I am wary of the ones sold as universal. Industrial seed oils and heavy refined sugar are worth reducing for nearly everyone. Beyond that it gets individual, and the only reliable way to find yours is a structured removal and reintroduction rather than guessing or removing everything at once.
Sleep debt
Short sleep raises inflammatory markers measurably, and it does it quickly. This is the driver most of my patients are least willing to look at, because it is the one that feels like a personal failing rather than a physiological input. It is not a character issue. It is an input.
Stress that never switches off
Cortisol is anti-inflammatory in the short term, which is exactly why chronic stress is a problem. Run it long enough and the system becomes less responsive to its own brakes. The stress that does damage is rarely dramatic, it is the steady low kind that you have stopped noticing.
Sitting still, and stored visceral fat
Visceral fat, the kind stored around the organs rather than under the skin, is metabolically active tissue that produces inflammatory signals of its own. This is the one that surprises fit people, because you can carry it while looking lean.
How do I know which one is mine?
You measure, then you change one thing at a time. Inflammatory markers such as hs-CRP give you a number to move. Combined with a careful history, they usually point at the one or two drivers doing most of the work for you, which is more useful than an overhaul you will abandon in three weeks.
What does progress look like?
Usually the order surprises people. Sleep and energy improve first, often within a couple of weeks. Digestion follows. Joint aches and the mental fog take longer, and the labs move on their own schedule after that. If nothing has shifted in six to eight weeks, we are working on the wrong driver, and that is worth knowing rather than pushing harder.
This is wellness and education, not medical treatment, and it works alongside your physician. If you want to know which driver is yours, that is what a consult is for.